Cleanrooms Case Studies
USP797 Pharmacy Compounding
USP 797 Pharmacy with Grade B Compounding and Formulation
Services Provided
- Cleanroom Design
- AHU System Design
- CFR21 Part 11 Monitoring System
- HEPA Filtered Pass Throughs & Cart Pass Through
- nora Cold Welded Seamless Rubber Flooring
- 2oC to 8oC Walk In Cooler
Pharmaceutical Manufacturing Upgrade
Cleanroom Upgrade – Existing Drywall Walls – ALUMA1 Cleanroom Wall System installed to provide new multiple room layouts, including Airlocks for cascading air pressures
Installation of the ALUMA-T Cleanroom Ceiling below the original Drywall Ceiling to provide a new lower ceiling increasing air change rates
Services Provided
- Cleanroom ALUMA1 Wall & Ceiling Systems
Pharmaceutical Pilot Manufacturing Suites
2011 Therapure Pilot Suites
Three Independent Suites:
- Grade A / ISO 5 for Filling, including modifications to existing OXATHERM & Nicomac Cleanrooms
- Independent Pilot Grade C / ISO 7 Cleanrooms, with separate Personnel Change Rooms and Air Locks, as well as Material Air Locks, with Access and Magnetic Locks.
Services Provided
- Complete Turn Key Design Build Including Architectural / Mechanical / Electrical & Structural
Pharmaceutical Packaging
Construction of the ISO 7 Pharmaceutical Packaging Rooms with the flexibility of the ALUMA1 Cleanroom Wall System allows for changes in configuration as required.
Services Provided
- Cleanroom Design
- Project Management and Protocol Training
Sunnybrook Health Sciences – DDL & cGMP Cleanrooms
Initial User Group Interviews to determine requirements for design within space allocated and budget for funding.
Services Provided
- ISO 5 Cleanrooms
- LED Tear Drop Light Fixtures
- ECM HEPA Fan Filter Modules save energy and reduced noise levels
McMaster University – Nuclear Research Building Cleanroom
ISO 7 & 8 Cleanroom
Services Provided
- ALUMA1 Cleanroom Walls & Ceiling
- Polypropylene Casework
- ECM HEPA Fan Filter Modules save energy, and allow one point electrical connection
- Custom HVAC System
Veterinary Vaccine Manufacturing
Assistance with original design and regulatory approval with CFIA.
BSL2 Enhanced with HEPA Filtration Supply and Return for Containment
Services Provided
- ALUMA1 Cleanroom Wall & Ceiling System
- Custom HVAC Systems
- 2 to 8oC Walk In Coolers
- 35oC Incubator
Nano Technology Cleanroom
Nanotechnology ISO 6 & 7 Cleanrooms Design Build Proposal
Custom HVAC System Designed in sections to allow delivery up elevator
Services Provided
- Hybrid Design Air Handling Units and Fan Filter Modules
- Custom Air Showers
- Grey Corridor for Gases and Equipment
- TEK-AIR Fume Hood Control
Downflow Booth
Therapure Biopharma required a downflow booth is a corner in three weeks.
Using the ALUMA1 Cleanroom Wall System, we were able to frame it up, and have the unit operational for testing in two weeks
The system uses the existing back wall, as well as the ceiling to be the plenum, and the new walls and ceiling installed to maintain the containment.
See our DOWNFLOW BOOTH DATA SHEET for more information
Services Provided
- ALUMA1 Walls & Windows
- ALUMA-T Ceiling allows access and sprinkler heads
- ECM HEPA Fan Filter Modules save energy, and allow one point connection
Optical Component Manufacturing
Services Provided
- ISO 5 Cleanrooms
- Cleanroom Design
- ECM HEPA Fan Filter Modules save energy and reduced noise levels
- Structural Catwalk for Fan Filter Module Access
Pharmaceutical Manufacturing & Packaging
Bracco – Hattiesburg Mississippi.
ISO 7 Cleanroom
Services Provided
- Initial Cleanroom Design Assistance
- Design Review with local trades and engineers
- Cleanroom in a Box components and Air Handling Unit
- On Site Cleanroom Protocol Training and On Site Management
Pharmaceutical Packaging
Design Assistance and Drawings
ISO 8 Cleanrooms
Services Provided
- HVAC System Design
- ALUMA1 Cleanroom and Self Supporting Ceiling
- Structural Support Inside Wall for Sliding Doors
- Return Air Design through Adjacent Rooms
Prollenium Technologies Inc.
ISO 5 Cleanroom – Wash Up and Packaging Roo
Services Provided
- Cleanroom Design and Programming
- Budgeting & Design to meet budget
- ECM HEPA Fan Filter Modules save energy and reduced noise levels
- Epoxy Floor
- Tear Drop Light Fixtures
- Return Air Upper Plenum
Fermentation Cleanroom BSL
BioVectra Inc. – Charlottetown – PEI
Cytotoxic Formulation Production
Services Provided
- Design and Approval Drawings
- Cleanroom in a Box including ALUMA1 Cleanroom Walls & Ceilings
- Custom AHU designed for Biological Containment
- ECM HEPA Fan Filter Modules for Production Suite & Airlocks
- On Site Cleanroom Protocol Training and On Site Management
Vaccine Manufacturing Cleanroom & Biological Safety Containment 2 Enhanced
Microbix Biosystems Inc. – Mississauga
Services Provided
- Air Handling Units Designed for internal platform saving major structural upgrades
- ALUMA1 Cleanroom Wall & Ceiling System
- 2 to 8oC Walk In Coolers
- 32oC Incubators
- MMA Flooring
- Complete Design Build and Fit Out of entire facility from offices to warehouse
Veterinary Pharmaceutical
Bimeda MTC ISO 7 Cleanroom
Services Provided
- Design and Approval Drawings
- ALUMA1 Cleanroom Wall & Ceiling System
- ALUMAfrp Wall Panels – 24′ Wall Height
- 2oC to 8oC Walk In Cooler
Compounding Pharmacy with Chemo BSC
Project 8 weeks from Design to Turn Over
Services Provided
- ALUMA1 Cleanroom Walls & Ceiling
- Stainless Steel Pass Throughs and Cart Through
- ECM HEPA Fan Filter Modules save energy, and allow one point connection
- Design Filtration Laminar Air Flow Workstations
- Combination Make Up Air – Cooling Unit
Pharmaceutical Packaging Delineation
The walls were required to delineate various packaging lines
Services Provided
- ALUMA1 Cleanroom Wall System
- Components Pre-Cut for ease of on site installation
- Lexan Windows
- 4′ X 8′ Double Doors
Pharmaceutical Membrane Manufacturing Cleanroom
Natrix Separations Inc. – Burlington
Services Provided
- Redesign of original configuration
- ALUMA1 Cleanroom Wall System with ALUMAfrp Panels
- 2 to 8oC Walk In Coolers
- Construction Project Management
- HVAC Design utilizing re-locatable components
- Polycrete NOVLAC Floor Coating
Dry Room
Spectral Diagnostics – Toronto
Design & Construction of a room to maintain less than 20% Relative Humidity
Services Provided
- System Conceptual Design
- ALUMA1 Cleanroom Wall System
- Custom Manufactured AHU with Bry-Air Desiccant Drier
- Carel Control System
University of Toronto – CADIFT Electronics ISO 5 Cleanroom
Mechanical Engineering Cleanroom
Services Provided
- Redesign of original configuration
- ECM HEPA Fan Filter Modules save energy and lower noise
- 80% Filter Coverage
- Existing Air Conditioning System used in design
Compounding Pharmacy
Chiron Compounding Pharmacy – Guelph
The Cleanrooms consist of a cluster of 5 ISO 7 Suites.
The project consisted of the design, installation of the Cleanrooms, and the HVAC System
Services Provided
- ALUMA1 Cleanroom Wall System
- 1 1/2 Inch Gasketed T Bar
- Tableting Room with Return Air HEPA Fan Filter Module and Strip Curtains
- Integrated HVAC System
- ECM HEPA Fan Filter Modules save energy and lower noise
Pharmaceutical Grade A Space
Pharmaceutical Grade A Space
ALUMA1 Snap Lock Pharma System
Services Provided
- Design Assistance to meet requirements for Entry & Exit Airlocks
- Reuse of Existing Supply Air Terminal HEPA Filters
- Installation of Return Air HEPA Filters
- Custom HEPA Filter for Exhaust from Exit Anterooms
Regenerative Medicine Cleanroom
Lake Superior Centre for Regenerative Medicine – Thunder Bay
ISO 4 Cleanroom.
Designed to fit in a very tight location, with no headroom
Custom AHU built to be above ceiling in adjacent room
Services Provided
- Complete Deign Build Cleanroom from Concept to Certification
UVic SEOS Trace Metals Cleanroom
Trace Metals Cleanrooms require that the room construction does not add contamination from metal elements.
The ALUMA1 wall system was used in these ISO Class 5 & 6 Cleanrooms. Utilizing ALUMAfrp wall panels and the Co-Extruded PVC Battens provided a metal free surface in the Cleanrooms and the Airstream
All other structural components were powder coated, as well as all components that were in contact with the airstream.View Site >
Services Provided
- Cleanroom Design Build
- Custom Make Up Air with 3 Temperature / Pressure Zones & Atmospheric Mercury Filtration
Aseptic Fill Suite
Hemosol – (Thearpure Biopharma)
The project included a progressive wall and ceiling system by Oxatherm, of France
6 Months from Initial Contact to Validated System by Health Canada
Services Provided
- Cleanroom Layout & Design
- HVAC System Design & Construction – Return Air Chase Saves $100,000
